Anthros are just what will naturally occur once human understanding of genetics advances sufficiently and gene therapy comes commercially available. It will take 0.5 seconds before the first person comes by saying "I want blue skin, E-cup and hooves!" Having sex with humans is not having sex with animals. Even if those humans had had their genes modified, they'd still count as humans.
Do not force your species centric view on individuals. They are only Human if they choose to self identify as such! You are literally worse than a centaur hybrid of Hitler and Stalin
So basically, my eharmony page will say: "Wants girl with blue skin, wings, and hooves". I predict a great majority of people copying aliens from Star Trek.
The hell? To imitate ST's aliens all you need is a comb and some wax. Depending on race you use the wax to lift or remove hair, sometimes you just put it on your skin and roll in dirt. That's about it.
Oh, I think we all know what's going to happen when genetic modification becomes possible... Spoiler: Slightly NSFW
Blue Skin? Hooves? Horn? Big Boobs? I think I got something for you that will fix that right up. NSFW >.> Spoiler Female Draenei can fill this void yes?